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  AEFI (ADVERSE EVENT FOLOWING IMMUNIZATION) is any untoward medical occurrence which follows immunization & which doesn’t necessarily have a casual relationship with the usage of vaccine.

  ADVERSE EVENTS ARE-

  1. REACTIONS INHERENT TO INCULATION- Local pain, swelling, nodules, redness, sterile abscess, tenderness [BCG- pain, swelling, redness]. General- Fever, malaise, headache.
  2. REACTIONS DUE TO FAULTY TECHNIQUE.
  3. REACTIONS DUE TO HYPERSENSITIVITY- Immediate- Anaphylactic shock. Delayed- Pyrexia, Arthralgia, Myalgia, Urticaria, oedema.
  4. NEUROLOGICAL INVOLVEMENT- Post vaccination encephalitis (BPL anti rabies vaccine). Guillain- Barre Syndrome (Swine Influenza vaccine). Sub-acute sclerosing pan encephalitis (Measles vaccine).
  5. PROVOCATIVE REACTIONS- Provocative polio (APT or PTAP against Diptheria).
  6. OTHERS- Damage to foetus (Rubella to pregnant woman). So, AEFI include events beyond side effects of vaccines.
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